The Pekosz Lab is a collaborative group that focuses on the phenotypic and antigenic characterization of respiratory viruses at the Bloomberg School of Public Health. As part of the CEIRR network and the Johns Hopkins CEIRR center (JH-CEIRR), the lab conducts seasonal surveillance and investigates population dynamics of circulating Influenza A and B viruses and SARS-CoV-2 in Baltimore, Taiwan, and Zambia.
We conduct research on the viral and host factors that contribute to temperature-dependent SARS-CoV-2 and Influenza replication using human nasal epithelial cell culture model systems (hNEC), which provide a more accurate analogue to infection of the upper respiratory system than traditional cell culture. Our research on viral and host factors includes investigations of mitochondrial dynamics, single-cell transcriptional responses, and IgG and IgM production in hNECs.
Additionally, we investigate temperature-dependent strain variability in enterovirus D68.
- New article: Gain-of-Function Research: Balancing Science and Security
- Virologists comment on the tenor of social media postings
- Dr. Jessica Resnick Presents Thesis Research
- Members of Pekosz Lab Acknowledged by Dr. Anthony Fauci for their role in the COVID-19 pandemic response
- The Pekosz Lab is looking for a postdoc!
Images (clockwise from left): 1. Lab photo taken July 2021 2. VeroE6 TMPRSS2 cells infected with SARS-CoV-2 (source: Dr. Eddy Anaya). Green is spike blue is nucleus 3. Filamentous influenza budding from a cell (source: Dr. Andrew Pekosz).
The Pekosz Lab 